Important Note: The following information is intended to supplement, not substitute for, the expertise and judgement of your physician, pharmacist or other healthcare professional.
Ibuprofen is used to relieve pain from various conditions such as headache, dental pain, menstrual cramps, muscle aches, or arthritis. It is also used to reduce fever and to relieve minor aches and pain due to the common cold or flu. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever.
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.
Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.
How to use Advil Migraine Oral If you are taking the over-the-counter product, read all directions on the product package before taking this medication. If your doctor has prescribed this medication, read the Medication Guide provided by your pharmacist before you start taking ibuprofen and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth, usually every 4 to 6 hours with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this drug. If you have stomach upset while taking this medication, take it with food, milk, or an antacid.
The dosage is based on your medical condition and response to treatment. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose or take this drug more often than directed by your doctor or the package label. For ongoing conditions such as arthritis, continue taking this medication as directed by your doctor.
When ibuprofen is used by children, the dose is based on the child's weight. Read the package directions to find the proper dose for your child's weight. Consult the pharmacist or doctor if you have questions or if you need help choosing a nonprescription product.
For certain conditions (such as arthritis), it may take up to two weeks of taking this drug regularly until you get the full benefit.
If you are taking this drug "as needed" (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.
If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away. If you are using the nonprescription product to treat yourself or a child for fever or pain, consult the doctor right away if fever worsens or lasts more than 3 days, or if pain worsens or lasts more than 10 days.
See also Warning section.
Upset stomach, nausea, vomiting, headache, diarrhea, constipation, dizziness, or drowsiness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, hearing changes (such as ringing in the ears), mental/mood changes, swelling of the ankles/feet/hands, sudden/unexplained weight gain, unexplained stiff neck, change in amount of urine, vision changes.
This drug may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including: dark urine, persistent nausea/vomiting/loss of appetite, stomach/abdominal pain, yellowing eyes/skin.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: cidofovir.
This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Some affected drugs include anti-platelet drugs such as clopidogrel, "blood thinners" such as enoxaparin/warfarin, bisphosphonates such as alendronate, corticosteroids such as prednisone, SSRI antidepressants such as fluoxetine/sertraline, among others.
Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (including aspirin, NSAIDs such as celecoxib, ketorolac, or naproxen). These drugs are similar to ibuprofen and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Daily use of ibuprofen may decrease aspirin's ability to prevent heart attack/stroke. Talk to your doctor about using a different medication (such as acetaminophen) to treat pain/fever. If you must take ibuprofen, talk to your doctor about possibly taking immediate-release aspirin (not enteric-coated/EC) while taking ibuprofen. Take ibuprofen at least 8 hours before or at least 30 minutes after your aspirin dose. Do not increase your daily dose of aspirin or change the way you take aspirin/other medications without your doctor's approval.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe stomach pain, trouble breathing, extreme drowsiness.
NOTES: If your doctor has prescribed this medication, do not share it with others.
Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Keep all regular medical and laboratory appointments.
MISSED DOSE: If you are taking this drug on a regular schedule (not just "as needed") and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised July 2011 Copyright(c) 2011 First DataBank, Inc.
Nonsteroidal anti-inflammatory drugs (including ibuprofen) may rarely increase the risk for a heart attack or stroke. The risk may be greater if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes), or with longer use. This drug should not be taken right before or after heart bypass surgery (CABG).
This drug may infrequently cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning at any time while taking this drug. Older adults may be at higher risk for this effect.
Stop taking ibuprofen and get medical help right away if you notice any of these rare but serious side effects: black/tarry stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, slurred speech, sudden vision changes.
Talk to your doctor or pharmacist about the benefits and risks of taking this drug.
Before taking ibuprofen, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before taking this medication, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps), heart disease (such as congestive heart failure, previous heart attack), high blood pressure, kidney disease, liver disease, severe loss of body water (dehydration), stroke, throat/stomach/intestinal problems (such as bleeding, heartburn, ulcers).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.
This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the effects of this drug, especially stomach/intestinal bleeding.
Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery. Discuss the risks and benefits with your doctor before using this medication.
This medication passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
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What conditions does Advil Migraine Oral treat?
Advil Migraine Oral is used to treat the following:
Painful Periods, Rheumatoid Arthritis, Joint Inflammatory Disease in Children and Young Adults, Joint Damage causing Pain and Loss of Function, Fever, Pain, Head Pain
Who should not take Advil Migraine Oral?
Check with your physician if you have any of the following:
Conditions:
Tobacco Smoking, Increased Cardiovascular Event Risk, Time Immediately after Coronary Bypass Surgery, Acute Thromboembolic Stroke, High Blood Pressure, Heart Attack, Chronic Heart Failure, Stomach or Intestinal Ulcer, Liver Problems, Bleeding of the Stomach or Intestines, Kidney Disease, Pregnancy, A Rupture in the Wall of the Stomach or Intestine, Blood Clotting Disorder, Habit of Drinking Too Much Alcohol
Allergies:
SALICYLATES NSAIDS
Does Advil Migraine Oral have side effects?
The following side effects are associated with Advil Migraine Oral:
Common side effects of Advil Migraine Oral:
| Rash | Severe |
| Dizzy | Less Severe |
| Feel Like Throwing Up | Less Severe |
| Heartburn | Less Severe |
| Stomach Cramps | Less Severe |
Infrequent side effects of Advil Migraine Oral:
| Ringing in the Ears | Severe |
| Itching | Severe |
| Visible Water Retention | Severe |
| Water Retention | Severe |
| Conditions of Excess Stomach Acid Secretion | Less Severe |
| Indigestion | Less Severe |
| Incomplete or Infrequent Bowel Movements | Less Severe |
| Loss of Appetite | Less Severe |
| Head Pain | Less Severe |
| Throwing Up | Less Severe |
| Gas | Less Severe |
| Diarrhea | Less Severe |
| Nervous | Less Severe |
| Easily Angered or Annoyed | Less Severe |
Rare side effects of Advil Migraine Oral:
| Depression | Severe |
| Yellowing of Skin or Eyes from Liver Problems | Severe |
| Numbness, Tingling or Pain of Hands or Feet | Severe |
| Double Vision | Severe |
| Blind Spot in the Eye | Severe |
| Blurred Vision | Severe |
| Problems with Eyesight | Severe |
| Pink Eye | Severe |
| Dry Eye | Severe |
| Vision Changes caused by Medications | Severe |
| Hearing Problem | Severe |
| High Blood Pressure | Severe |
| Heart Attack | Severe |
| Abnormal Heart Rhythm | Severe |
| Chronic Heart Failure | Severe |
| Stroke | Severe |
| Meningitis Not Caused by an Infection | Severe |
| Vasculitis | Severe |
| Inflammation of the Nose | Severe |
| Vocal Cord Swelling | Severe |
| Bronchospasm | Severe |
| Canker Sore | Severe |
| Ulcers of Esophagus | Severe |
| Stomach Ulcer | Severe |
| Ulcer from Stomach Acid | Severe |
| Stomach or Intestinal Ulcer | Severe |
| Burning Stomach | Severe |
| Hepatitis | Severe |
| Hepatitis caused by Drugs | Severe |
| Acute Inflammation of the Pancreas | Severe |
| Red Blood in Bowel Movement | Severe |
| Bleeding of the Stomach or Intestines | Severe |
| Kidney Damage | Severe |
| Renal Tubular Necrosis | Severe |
| Kidney Failure | Severe |
| Renal Papillary Necrosis | Severe |
| Kidney Disease | Severe |
| Inflammation of the Bladder | Severe |
| Bloody Urine | Severe |
| Bleeding Not Related to Menstrual Period | Severe |
| Inflammation of Skin caused by an Allergy | Severe |
| Inflammation of the Skin with Blisters | Severe |
| Erythema Multiforme | Severe |
| Toxic Epidermal Necrolysis | Severe |
| Stevens-Johnson Syndrome | Severe |
| Skin Rash with Sloughing | Severe |
| Hives | Severe |
| Lupus-Like Syndrome | Severe |
| Mental Impairment | Severe |
| Hallucination | Severe |
| Nosebleed | Severe |
| Wheezing | Severe |
| Trouble Breathing | Severe |
| Chest Pain | Severe |
| Chest Tightness | Severe |
| Throwing Up Blood | Severe |
| Excess Urination | Severe |
| Abnormal Liver Function Tests | Severe |
| Life Threatening Allergic Reaction | Severe |
| Giant Hives | Severe |
| Reaction due to an Allergy | Severe |
| Allergic Reaction causing Serum Sickness | Severe |
| A Rupture in the Wall of the Stomach or Intestine | Severe |
| Hemolytic Anemia | Severe |
| Acquired Decrease of All Cells in the Blood | Severe |
| Low Blood Counts due to Bone Marrow Failure | Severe |
| Anemia | Severe |
| Decreased Blood Platelets | Severe |
| Deficiency of Granulocytes a Type of White Blood Cell | Severe |
| Decreased White Blood Cells | Severe |
| Decreased Neutrophils a Type of White Blood Cell | Severe |
| Increased Eosinophils in the Blood | Severe |
| Confused | Severe |
| Mood Changes | Severe |
| Hemorrhage of Blood Under the Skin | Less Severe |
| Dry Mouth | Less Severe |
| Mouth Irritation | Less Severe |
| Sun-Sensitive Skin | Less Severe |
| Drowsiness | Less Severe |
| Chronic Trouble Sleeping | Less Severe |
| Temporary Redness of Face and Neck | Less Severe |
| Fast Heartbeat | Less Severe |
| Heart Throbbing or Pounding | Less Severe |
| Anxious | Less Severe |
Should I avoid certain foods while taking Advil Migraine Oral?
There is no food interaction information available for Advil Migraine Oral at this time. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Does Advil Migraine Oral interact with other medications?
Advil Migraine Oral may interact with the following medications
Severe Interactions of Advil Migraine Oral:
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
SELECTED NEPHROTOXIC AGENTS/CIDOFOVIR
NSAID;ASPIRIN (NON-INJECTABLE)/KETOROLAC (INJECTABLE)
NSAID;ASPIRIN/KETOROLAC (NON-INJECTABLE)
Serious Interactions of Advil Migraine Oral:
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
NSAIDS/APIXABAN; RIVAROXABAN
NSAIDS/DABIGATRAN
NSAIDS/ORAL SODIUM PHOSPHATE
SELECTED NSAIDS; ASPIRIN/PEMETREXED
NSAIDS/METHOTREXATE
Moderate Interactions of Advil Migraine Oral:
These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
NSAIDS/LOOP DIURETICS
NSAIDS/LITHIUM
NONSTEROIDAL ANTI-INFLAMMATORY DRUGS/BETA-BLOCKERS
SELECTED NSAIDS/PROBENECID
NSAIDS/ERLOTINIB
IBUPROFEN/ASPIRIN
NSAIDS/TENOFOVIR
NSAIDS/DROSPIRENONE
NSAIDS; ASPIRIN/SSRIS; SNRIS
NSAIDS/SELECTED PLATELET AGGREGATION INHIBITORS
NSAIDS/HEPARINS
NSAIDS/ANTICOAGULANTS
NSAIDS/CYCLOSPORINE
IBUPROFEN; INDOMETHACIN/DIGOXIN
SELECTED NSAIDS/TRIAMTERENE; AMILORIDE
SELECTED NSAIDS/ACE INHIBITORS; ARBS